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VHD Fact Sheet

by Darice Heishman

Quick Facts:

  • Known as RCD (Rabbit Calicivirus Disease) or VHD (Viral Hemorrhagic Disease)
  • It is a highly infectious viral disease that can infect domestic rabbits.
  • It is not known to effect humans or other animals, including cottontails and jackrabbits.

Incubation:

  • The incubation period is approximately 24 to 48 hours after exposure.

Transmission:

  • This virus can be transmitted by contact with infected rabbits, rabbit products (including pelts and carcasses), contaminated clothing, cages, and feeders.
  • Infected rabbits that may recover become carriers and can shed virus for at least 4 weeks.
  • The virus can survive on inanimate objects for up to 3 weeks.

Symptoms:

Young and adult rabbits can die suddenly within 6 - 24 hours of onset of fever with few clinical signs.

Symptoms may include: -
  • high temperature (2-4 degrees over the normal temp)
  • difficulty breathing, lethargy, lack of appetite
  • bleeding from nose/rectum/mouth
  • foamy nasal discharge
  • neurologic signs (excitement, lack of coordination, and abnormal head position due to spasms of neck muscles.)
  • The virus can damage the liver, intestines, lymphatic tissue and causes terminal massive blood clots.

Treatment:

  • There is no treatment currently available; death rate can range from 50 - 100 percent in exposed rabbits.

Prevention:

  • There is currently no vaccine legally available in the United States.
  • Be cautious and quarantine new rabbits and rabbits coming back from shows for at least 5 days.
  • If exposure to the virus is suspected, thoroughly clean then disinfect all housing and equipment.
Disinfectant solutions to inactivate the virus:
  • A solution of 10-percent household bleach (exposed a minimum of 10 minutes)
  • 2-percent 1 Stroke Environ (Steris Corporation, St. Louis, Missouri)
  • 0.5-percent sodium

If you suspect RCD/VHD:

  • A necropsy should be done on any rabbit that dies suspiciously or showed RCD clinical signs.
  • Veterinarians and rabbit owners who suspect that a rabbit has this virus should immediately contact their MA State Veterinarian, Lorraine O'Connor at 617-727-3018 or Federal animal health authorities.

US Dept. of Ag, Animal and Plant Health Inspection Service

Veterinary Services, Emergency Programs
(301) 734-8073 (800) 940-6524
EMOC@ APHIS.USDA.GOV

VHD in the US Coalition

www.vhdcoalition.org
(800) 906-2445
vhd@kindplanet.org

Information from the APHIS Veterinary Services "Rabbit Calicivirus Disease" Factsheet, April 2000

Reference - DiGiacomo, R. and Mare, C. (1994). Viral Diseases In "The Biology of the Laboratory Rabbit." 2nd Edition

( P. Manning, D. Ringler, C. Newcomer eds.) pp 193-195. 20 Academic Press, San Diego, CA